E-cadherin endocytosis promotes non-canonical EGFR:STAT signalling to induce cell death and inhibit heterochromatinisation

Ramirez Moreno, M. orcid.org/0000-0003-1559-8976, Quinton, A., Jacobsen, E. orcid.org/0009-0008-7963-5557 et al. (3 more authors) (2025) E-cadherin endocytosis promotes non-canonical EGFR:STAT signalling to induce cell death and inhibit heterochromatinisation. PLoS Genetics, 21 (7). e1011781. ISSN: 1553-7390

Abstract

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Item Type: Article
Authors/Creators:
Editors:
  • Wappner, P.
Copyright, Publisher and Additional Information:

© 2025 Ramirez Moreno et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Keywords: Biochemistry and Cell Biology; Biological Sciences; Normal biological development and functioning; Biological and endogenous factors; Cancer; Generic health relevance
Dates:
  • Accepted: 23 June 2025
  • Published (online): 21 July 2025
  • Published: 21 July 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 06 Aug 2025 11:28
Last Modified: 06 Aug 2025 11:28
Status: Published
Publisher: Public Library of Science (PLoS)
Refereed: Yes
Identification Number: 10.1371/journal.pgen.1011781
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Open Archives Initiative ID (OAI ID):

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