Bracken, M.L., Moyo-Gwete, T., Sookai, S. et al. (2 more authors) (2025) Copper pincer targets SARS-CoV-2 Omicron, Delta, and Wild-Type receptor binding domains. Inorganic Chemistry Communications, 179 (Part 2). 114887. ISSN: 1387-7003
Abstract
A novel copper(II) pincer was synthesized and crystallized to form a metallocycle hexamer. The metal chelate was designed to target solvent-exposed amino acid residues on the SARS-CoV-2 spike protein with the potential to act as a chemotherapeutic agent in the treatment of COVID-19.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2025 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/). |
Keywords: | Copper; Pincer ligands; Covid; SARS; Therapeutic; Fluorescence |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Physical Chemistry (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 24 Jul 2025 11:53 |
Last Modified: | 24 Jul 2025 11:53 |
Published Version: | https://www.sciencedirect.com/science/article/pii/... |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.inoche.2025.114887 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:229410 |
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