PIEZO1 mechanical insensitivity in generalized lymphatic dysplasia with the potential for pharmacological rescue

Ludlow, M., Povstyan, O. V., Linley, D. M. et al. (20 more authors) (2025) PIEZO1 mechanical insensitivity in generalized lymphatic dysplasia with the potential for pharmacological rescue. iScience, 28 (8). 113110. ISSN: 2589-0042

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Ludlow, M.
  • Povstyan, O. V.
  • Linley, D. M.
  • Martin-Almedina, S.
  • Revill, C.
  • Cuthbertson, K.
  • Smith, K. A.
  • Fay, E.
  • Fotiou, E.
  • Bush, A.
  • Hogg, C.
  • Linden, T.
  • Tan, N. B.
  • White, S. M.
  • Del Rey Jimenez, J. C.
  • Sackey, E.
  • Dempsey, E.
  • Mansour, S.
  • Parsonage, G.
  • Kalli, A. C.
  • Foster, R.
  • Ostergaard, P.
  • Beech, D. J. ORCID logo https://orcid.org/0000-0002-7683-9422
Copyright, Publisher and Additional Information:

© 2025 The Author(s). This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

Dates:
  • Accepted: 10 July 2025
  • Published (online): 15 July 2025
  • Published: 15 August 2025
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds)
Funding Information:
Funder
Grant number
British Heart Foundation
RG/17/11/33042
British Heart Foundation
FS/4yPhD/F/21/34153
NIHR National Inst Health Research
Not Known
Wellcome Trust
110044/Z/15/Z
Depositing User: Symplectic Publications
Date Deposited: 10 Jul 2025 09:05
Last Modified: 12 Aug 2025 13:29
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.isci.2025.113110
Open Archives Initiative ID (OAI ID):

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