Programmable 2D metal‐organic framework nanosheets for enzyme‐like hydrolysis of large proteins (Adv. Funct. Mater. 22/2025)

Metal-Organic Framework Nanosheets

In article number 2504117, Jonathan A. Foster, Tatjana N. Parac-Vogt, and co-workers develop metal–organic framework nanosheets with large surface areas as a new class of heterogeneous nanozymes for peptide bond hydrolysis, providing superior active site accessibility and enhanced catalytic reactivity toward a wide range of peptides and proteins.