A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis

Schmidt, W.A., Dasgupta, B., Sloane, J. et al. (13 more authors) (2023) A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis. Arthritis Research & Therapy, 25. 199. ISSN 1478-6354

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Schmidt, W.A.
  • Dasgupta, B.
  • Sloane, J.
  • Giannelou, A.
  • Xu, Y.
  • Unizony, S.H.
  • Mackie, S.L. ORCID logo https://orcid.org/0000-0003-2483-5873
  • Gonzalez-Gay, M.A.
  • Spiera, R.
  • Warrington, K.J.
  • Villiger, P.M.
  • Nivens, M.C.
  • Akinlade, B.
  • Lin, Y.
  • Buttgereit, F.
  • Stone, J.H.
Copyright, Publisher and Additional Information:

© The Author(s) 2023. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Keywords: Sarilumab; Giant cell arteritis; Glucocorticoids; Interleukin-6; Sustained remission
Dates:
  • Accepted: 21 September 2023
  • Published (online): 16 October 2023
  • Published: 16 October 2023
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 04 Jun 2025 16:11
Last Modified: 04 Jun 2025 16:11
Status: Published
Publisher: BioMed Central
Identification Number: 10.1186/s13075-023-03177-6
Related URLs:
Open Archives Initiative ID (OAI ID):

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