Plasmin cleavage of β2-glycoprotein I alters its structure and ability to bind to pathogenic antibodies

Bradford, H.F., Lalaurie, C.J., Gor, J. et al. (10 more authors) (2025) Plasmin cleavage of β2-glycoprotein I alters its structure and ability to bind to pathogenic antibodies. Journal of Thrombosis and Haemostasis, 23 (6). pp. 1864-1878. ISSN 1538-7933

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Bradford, H.F.
  • Lalaurie, C.J.
  • Gor, J.
  • Gao, X.
  • Pericleous, C.
  • Perkins, S.J.
  • Britt, H. ORCID logo https://orcid.org/0000-0001-8510-0331
  • Thalassinos, K.
  • Giles, I.
  • Rahman, A.
  • Delcea, M.
  • Dalby, P.A.
  • McDonnell, T.C.R.
Copyright, Publisher and Additional Information:

© 2025 The Author(s). This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords: autoantigens; β2-glycoprotein I; cleavage; plasmin; structural change
Dates:
  • Accepted: 11 February 2025
  • Published (online): 24 February 2025
  • Published: June 2025
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 03 Jun 2025 10:09
Last Modified: 03 Jun 2025 10:09
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.jtha.2025.02.015
Related URLs:
Open Archives Initiative ID (OAI ID):

Export

Statistics