Spatial transcriptomics resolves tissue-level molecular effects of denosumab therapy in a randomized clinical trial for periprosthetic osteolysis

Dunning, M.J. orcid.org/0000-0002-8853-9435, LeMaitre, C.L. and Wilkinson, J.M. orcid.org/0000-0001-5577-3674 (2025) Spatial transcriptomics resolves tissue-level molecular effects of denosumab therapy in a randomized clinical trial for periprosthetic osteolysis. In: Orthopaedic Proceedings. The British Hip Society (BHS) Meeting 2025, 05-07 Mar 2025, Harrogate, England. British Editorial Society of Bone & Joint Surgery , p. 48.

Metadata

Item Type: Proceedings Paper
Authors/Creators:
Copyright, Publisher and Additional Information:

© 2025
Keywords: Biological Sciences; Biomedical and Clinical Sciences; Engineering; Biomedical Engineering; Biotechnology; Clinical Trials and Supportive Activities; Aging; Genetics; Clinical Research; Osteoporosis; Musculoskeletal
Dates:
  • Published (online): 31 March 2025
  • Published: 31 March 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield)
Funding Information:
Funder
Grant number
SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST
STH15714
MRC-ARTHRITIS RESEARCH UK CENTRE FOR INTEGRATED RESEARCH INTO MUSCULOSKELETAL AGEING
UNSPECIFIED
Depositing User: Symplectic Sheffield
Date Deposited: 02 May 2025 12:03
Last Modified: 02 May 2025 12:03
Status: Published
Publisher: British Editorial Society of Bone & Joint Surgery
Refereed: Yes
Identification Number: 10.1302/1358-992x.2025.2.048
Open Archives Initiative ID (OAI ID):

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