Murray, Laura May, Hayes, April, Snape, Jason orcid.org/0000-0002-6634-8443 et al. (3 more authors) (2024) Co-selection for antibiotic resistance by environmental contaminants. npj antimicrobials and resistance. 9. ISSN 2731-8745
Abstract
The environment is increasingly recognised as a hotspot for the selection and dissemination of antibiotic resistant bacteria and antibiotic resistance genes. These can be selected for by antibiotics and non-antibiotic agents (such as metals and biocides), with the evidence to support this well established by observational and experimental studies. However, there is emerging evidence to suggest that plant protection products (such as herbicides), and non-antibiotic drugs (such as chemotherapeutic agents), can also co-select for antibiotic resistance. This review aims to provide an overview of four classes of non-antibiotic agents (metals, biocides, plant protection products, and non-antibiotic drugs) and how they may co-select for antibiotic resistance, with a particular focus on the environment. It also aims to identify key knowledge gaps that should be addressed in future work, to better understand these potential co-selective agents.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024. The Author(s). |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Environment and Geography (York) |
Depositing User: | Pure (York) |
Date Deposited: | 30 Apr 2025 13:10 |
Last Modified: | 30 Apr 2025 13:10 |
Published Version: | https://doi.org/10.1038/s44259-024-00026-7 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1038/s44259-024-00026-7 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:226021 |
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Description: Co-selection for antibiotic resistance by environmental contaminants
Licence: CC-BY 2.5