British Society of Gastroenterology guidelines for diagnosis and management of autoimmune hepatitis

Abstract

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. The last British Society of Gastroenterology (BSG) guideline for the management of AIH was published in 2011. Since then, our understanding of AIH has advanced in many areas. This update to the previous guideline was commissioned by the BSG and developed by a multidisciplinary group. The aim of this guideline is to review and summarise the current evidence, in order to inform and guide diagnosis and management of patients with AIH and its variant syndromes. The main focus is on AIH in adults, but the guidelines should also be relevant to older children and adolescents.

Metadata

Item Type:	Article
Authors/Creators:	Gleeson, D. https://orcid.org/0000-0001-8714-2367 Bornand, R. Brownlee, A. Dhaliwal, H. Dyson, J.K. Hails, J. Henderson, P. Kelly, D. Mells, G.F. Miquel, R. Oo, Y.H. Sutton, A. https://orcid.org/0000-0003-2449-2516 Yeoman, A. Heneghan, M.A.
Copyright, Publisher and Additional Information:	© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Keywords:	autoimmune hepatitis; autoimmune liver disease; drug toxicity; liver
Dates:	Submitted: 22 June 2024 Accepted: 22 October 2024 Published (online): 1 April 2025 Published: September 2025
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Date Deposited:	17 Apr 2025 13:18
Last Modified:	14 Nov 2025 16:29
Status:	Published
Publisher:	BMJ
Refereed:	Yes
Identification Number:	10.1136/gutjnl-2024-333171
Related URLs:	PubMed URL
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:225573

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British Society of Gastroenterology guidelines for diagnosis and management of autoimmune hepatitis

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