Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies

Smith, C. E. L., Streets, A. J., Lake, A. V. R. et al. (14 more authors) (2025) Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies. Communications Medicine, 5. 129. ISSN 2730-664X

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Smith, C. E. L.
  • Streets, A. J.
  • Lake, A. V. R.
  • Natarajan, S.
  • Best, S. K.
  • Szymanska, K.
  • Karwatka, M.
  • Stevenson, T.
  • Trowbridge, R.
  • Grant, G.
  • Grellscheid, S. N.
  • Foster, R.
  • Morrison, C. G.
  • Mavria, G.
  • Bond, J.
  • Ong, A. C. M.
  • Johnson, C. A. ORCID logo https://orcid.org/0000-0002-2979-8234
Copyright, Publisher and Additional Information:

© The Author(s) 2025. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

Dates:
  • Accepted: 4 April 2025
  • Published (online): 19 April 2025
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds)
Funding Information:
Funder
Grant number
EU - European Union
HEALTH-F5-2010-241955
Action Medical Research Vincent House
GN2628
Kidney Research UK Account Ref: UNI008
PKD_RP_006_20211124
Newlife Charity for Disabled Children
12-13/11
BBSRC (Biotechnology & Biological Sciences Research Council)
BB/P007791/1
Depositing User: Symplectic Publications
Date Deposited: 15 Apr 2025 14:32
Last Modified: 08 May 2025 15:33
Status: Published online
Publisher: Springer
Identification Number: 10.1038/s43856-025-00847-1
Open Archives Initiative ID (OAI ID):

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