Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q

Stavish, D., Price, C.J., Gelezauskaite, G. et al. (19 more authors) (2024) Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q. Stem Cell Reports, 19 (8). pp. 1217-1232. ISSN 2213-6711

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Item Type: Article
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© 2024 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: MDM4; culture conditions; genetic changes; genome damage; human pluripotent stem cells; Humans; Chromosomes, Human, Pair 1; Pluripotent Stem Cells; Cell Cycle Proteins; Proto-Oncogene Proteins; Cell Culture Techniques; Apoptosis; Feeder Cells; Cell Line; Cells, Cultured
Dates:
  • Published: 13 August 2024
  • Published (online): 3 July 2024
  • Accepted: 5 June 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Funding Information:
Funder
Grant number
MEDICAL RESEARCH COUNCIL
MR/R015724/1
MEDICAL RESEARCH COUNCIL
MR/X000028/1
MEDICAL RESEARCH COUNCIL
MR/X007979/1
Depositing User: Symplectic Sheffield
Date Deposited: 24 Mar 2025 11:30
Last Modified: 24 Mar 2025 11:30
Published Version: https://doi.org/10.1016/j.stemcr.2024.06.003
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.stemcr.2024.06.003
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