Retinal cells derived from patients with DRAM2-dependent CORD21 dystrophy exhibit key lysosomal enzyme deficiency and lysosomal content accumulation

Tsikandelova, R., Galo, E., Cerniauskas, E. et al. (18 more authors) (2024) Retinal cells derived from patients with DRAM2-dependent CORD21 dystrophy exhibit key lysosomal enzyme deficiency and lysosomal content accumulation. Stem Cell Reports, 19 (8). pp. 1107-1121. ISSN 2213-6711

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Tsikandelova, R.
  • Galo, E.
  • Cerniauskas, E.
  • Hallam, D.
  • Georgiou, M.
  • Cerna-Chavez, R.
  • Atkinson, R.
  • Palmowski, P.
  • Burté, F.
  • Davies, T.
  • Steel, D.H.
  • McKibbin, M.
  • Bond, J. ORCID logo https://orcid.org/0000-0001-5390-5688
  • Haggarty, J.
  • Whitfield, P.
  • Korolchuk, V.
  • Armstrong, L.
  • Yang, C.
  • Dorgau, B.
  • Kurzawa-Akanbi, M.
  • Lako, M.
Copyright, Publisher and Additional Information:

© 2024 The Author(s). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)

Keywords: DRAM2; CORD21; lysosomes; vesicular transport; autophagy; retinal organoids; RPE cells; lipd metabolism
Dates:
  • Published: 13 August 2024
  • Published (online): 3 July 2024
  • Accepted: 4 June 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 14 Mar 2025 10:22
Last Modified: 14 Mar 2025 10:22
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.stemcr.2024.06.002
Related URLs:
Open Archives Initiative ID (OAI ID):

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