Tan, A.T.H., Johansson, H., Harvey, N.C. et al. (4 more authors) (2024) Assessment of fracture risk with FRAX and FRAXplus. Gaceta Médica de México, 160 (4). pp. 363-373. ISSN 0016-3813
Abstract
FRAX®, a risk calculator that provides individualized 10-year probabilities of hip and major osteoporotic fracture, has been widely used for fracture risk assessment since its launch in 2008. It is now incorporated into very many guidelines worldwide to inform osteoporosis management. In this review, we explore the development of FRAX and how it enhances fracture risk prediction as compared to use of bone mineral density alone, as well as approaches to utilizing FRAX in determining intervention and assessment thresholds. We also discuss the limitations of FRAX and the arithmetic adjustments that have been proposed to address these. The introduction of FRAXplus® includes these adjustments on a web-based platform for ease of application to enhance treatment decisions in osteoporosis.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 Academia Nacional de Medicina de México, A.C.. Published by Permanyer. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
Keywords: | Epidemiology; Epidemiología; Evaluación de riesgos; FRAX; FRAXplus; Fracture probability; Osteoporosis; Probabildad de fractura; Risk assessment; Humans; Risk Assessment; Osteoporotic Fractures; Bone Density; Osteoporosis; Hip Fractures |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 28 Feb 2025 15:27 |
Last Modified: | 28 Feb 2025 15:40 |
Status: | Published |
Publisher: | Publicidad Permanyer, SLU |
Refereed: | Yes |
Identification Number: | 10.24875/gmm.24000107 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:223852 |