Structure and function of MDM2 and MDM4 in health and disease

Zhu, I.Y. orcid.org/0009-0004-2407-0297, Lloyd, A., Critchley, W.R. orcid.org/0000-0002-2707-4080 et al. (7 more authors) (2025) Structure and function of MDM2 and MDM4 in health and disease. The Biochemical journal, 482 (04). pp. 241-262. ISSN 0264-6021

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Item Type: Article
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© 2025 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).

Keywords: MDM2, MDM4, E3 ubiquitin ligase, p53, 26S proteasome, cancer
Dates:
  • Published: 17 February 2025
  • Published (online): 17 February 2025
  • Accepted: 31 January 2025
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Cardiovascular Science (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 24 Feb 2025 09:26
Last Modified: 24 Feb 2025 09:26
Published Version: https://portlandpress.com/biochemj/article/482/04/...
Status: Published
Publisher: Portland Press Ltd
Identification Number: 10.1042/bcj20240757
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