Optimising outcomes for adults with cystic fibrosis taking CFTR modulators by individualising care: personalised data linkage to understand treatment optimisation (PLUTO), a novel clinical framework

• Sandler, R.D. https://orcid.org/0000-0002-6933-9921
• Anderson, A.
• Barnett, T.
• Bourke, S.J.
• Cameron, S. https://orcid.org/0009-0003-2818-2379
• Chapman, S.J.
• Choyce, J. https://orcid.org/0000-0002-2813-7557
• Daniels, T. https://orcid.org/0000-0002-5249-5100
• Daniels, T.
• Dawson, S.
• Doe, S.
• Dooney, M.
• Echevarria, C.
• Galey, P. https://orcid.org/0009-0005-5338-3572
• Fitch, G. https://orcid.org/0009-0002-4891-5691
• Lai, L.Y.H.
• Nightingale, J.A. https://orcid.org/0000-0002-8978-2840
• Thomas, M.
• Thompson, R.
• Whitehouse, J.
• Warnock, L.
• Waine, D. https://orcid.org/0000-0002-4017-4588
• Withers, N. https://orcid.org/0000-0002-5326-0258
• Hoo, Z.H. https://orcid.org/0000-0002-7067-3783
• Wildman, M.J. https://orcid.org/0000-0002-1658-881X

© 2025 The Authors. Except as otherwise noted, this author-accepted version of a journal article published in Respiratory Medicine is made available via the University of Sheffield Research Publications and Copyright Policy under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/

• Published: April 2025
• Published (online): 14 February 2025
• Accepted: 11 February 2025
• Submitted: 28 August 2024