Characterisation and analysis of mRNA critical quality attributes using liquid chromatography based methods

Webb, A.L.J., Welbourne, E.N. orcid.org/0000-0001-7328-4591, Evans, C.A. et al. (1 more author) (2025) Characterisation and analysis of mRNA critical quality attributes using liquid chromatography based methods. Journal of Chromatography A, 1745. 465724. ISSN 0021-9673

Abstract

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Item Type: Article
Authors/Creators:
Copyright, Publisher and Additional Information:

© 2025 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by- nc-nd/4.0/).

Keywords: Critical quality attributes; HPLC; Mass spectrometry; mRNA; mRNA vaccines/therapeutics
Dates:
  • Published: 29 March 2025
  • Published (online): 28 January 2025
  • Accepted: 24 January 2025
  • Submitted: 20 October 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > School of Chemical, Materials and Biological Engineering
The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Chemical and Biological Engineering (Sheffield)
Funding Information:
Funder
Grant number
COALITION FOR EPIDEMIC PREPAREDNESS INNOVATIONS
UNSPECIFIED
Engineering and Physical Sciences Research Council
2735174
Engineering and Physical Sciences Research Council
2900494
Depositing User: Symplectic Sheffield
Date Deposited: 19 Feb 2025 15:06
Last Modified: 19 Feb 2025 15:06
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.chroma.2025.465724
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Sustainable Development Goals:
  • Sustainable Development Goals: Goal 3: Good Health and Well-Being
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