He, Yaji, Shao, Ximing, Liu, Chang et al. (4 more authors) (2025) Diverse Frontoparietal Connectivity Supports Semantic Prediction and Integration in Sentence Comprehension. Journal of neuroscience. e1404242024. ISSN 1529-2401
Abstract
Predictive processing in the parietal, temporal, frontal, and sensory cortex allows us to anticipate future meanings to maximize the efficiency of language comprehension, with the temporoparietal junction (TPJ) and inferior frontal gyrus (IFG) thought to be situated toward the top of a predictive hierarchy. Although the regions underpinning this fundamental brain function are well-documented, it remains unclear how they interact to achieve efficient comprehension. To this end, we recorded functional magnetic resonance imaging (fMRI) in 22 participants (11 males) while they comprehended sentences presented part by part, in which we manipulated the constraint provided by sentential contexts on upcoming semantic information. Using this paradigm, we examined the connectivity patterns of bilateral TPJ and IFG during anticipatory phases (i.e., before the onset of targets) and integration phases (i.e., after the onset of targets). When upcoming semantic content was highly predictable in strong constraint contexts, both the left TPJ and bilateral IFG showed stronger visual coupling, while the right TPJ showed stronger connectivity with regions within control, default mode, and visual networks, including the IFG, parahippocampal gyrus, posterior cingulate, and fusiform gyrus. These connectivity patterns were weaker when predicted semantic content appeared, in line with predictive coding theory. Conversely, for less-predictable content, these connectivity patterns were stronger during the integration phase. Overall, these results suggest that both top-down semantic prediction and bottom-up integration during predictive processing are supported by flexible coupling of frontoparietal regions with control, memory, and sensory systems.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 He et al. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 13 Feb 2025 05:33 |
Last Modified: | 04 Mar 2025 00:10 |
Published Version: | https://doi.org/10.1523/JNEUROSCI.1404-24.2024 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1523/JNEUROSCI.1404-24.2024 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:223266 |
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Description: Diverse Frontoparietal Connectivity Supports Semantic Prediction and Integration in Sentence Comprehension
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