Chaplin, H. orcid.org/0000-0002-9402-9669, Simpson, C., Wilkins, K. et al. (9 more authors)
(2025)
Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals.
British Journal of Health Psychology, 30 (1).
e12780.
ISSN 1359-107X
Abstract
Objectives
This study aims to explore patients' and clinicians' understanding and experiences of refractory disease (RD) and persistent physical and emotional symptoms (PPES) in patients with inflammatory arthritis (IA), namely rheumatoid arthritis or polyarticular juvenile idiopathic arthritis from their perspectives through interviews and/or focus groups.
Design
A qualitative study was conducted, following a pragmatic epistemology approach with framework analysis employed.
Methods
Semi-structured interviews or focus groups with IA patients (n = 25) and multi-disciplinary rheumatology HCPs (n = 32) were conducted at one time point to obtain participants respective understanding and experiences of managing RD/PPES, and its impact on the patient-professional relationship.
Results
Three key themes were identified from both patients and professionals' experiences of RD/PPES: (1) relevant treatment experiences, (2) symptoms (with or without inflammation) and (3) impact: physical, psychological and social. These themes included 28 specific categories that would be considered as components characterizing RD/PPES, most common to both patients and HCPs with six being patient-specific and only one HCP-specific. The specific biopsychosocial symptoms and impacts of RD/PPES pertain to pain, fatigue, stiffness, joint involvement and physical, psychological and social functioning and quality of life, covering disease-related distress, mobility and independence. Wider influential factors such as comorbidities, non-adherence, health/medication beliefs and behaviours and social support were also identified.
Conclusion
Common persistent symptoms that have both mental and physical impact characterize RD/PPES in IA and therefore a more integrated holistic approach to treatment is needed from multi-disciplinary HCPs, including health psychologists.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: | This paper has 12 authors. You can scroll the list below to see them all or them all.
|
Copyright, Publisher and Additional Information: | © 2025 The Author(s). British Journal of Health Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
Keywords: | inflammatory arthritis; multi‐disciplinary health care professionals; persistent symptoms; qualitative; refractory disease; Humans; Female; Male; Qualitative Research; Middle Aged; Adult; Arthritis, Rheumatoid; Focus Groups; Arthritis, Juvenile; Aged; Interviews as Topic; Health Personnel; Young Adult |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 31 Jan 2025 10:29 |
Last Modified: | 31 Jan 2025 10:29 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1111/bjhp.12780 |
Related URLs: | |
Sustainable Development Goals: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:222560 |