Single-cell analysis of bronchoalveolar cells in inflammatory and fibrotic post-COVID lung disease

Mehta, P., Sanz-Magallón Duque de Estrada, B., Denneny, E.K. et al. (14 more authors) (2024) Single-cell analysis of bronchoalveolar cells in inflammatory and fibrotic post-COVID lung disease. Frontiers in Immunology, 15. 1372658. ISSN 1664-3224

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Mehta, P.
  • Sanz-Magallón Duque de Estrada, B.
  • Denneny, E.K.
  • Foster, K.
  • Turner, C.T.
  • Mayer, A.
  • Milighetti, M.
  • Platé, M.
  • Worlock, K.B.
  • Yoshida, M.
  • Brown, J.S.
  • Nikolić, M.Z.
  • Chain, B.M.
  • Noursadeghi, M.
  • Chambers, R.C.
  • Porter, J.C.
  • Tomlinson, G.S. ORCID logo https://orcid.org/0000-0003-4342-3161
Copyright, Publisher and Additional Information:

© 2024 Mehta, Sanz-Magallón Duque de Estrada, Denneny, Foster, Turner, Mayer, Milighetti, Platé, Worlock, Yoshida, Brown, Nikolić, Chain, Noursadeghi, Chambers, Porter and Tomlinson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. http://creativecommons.org/licenses/by/4.0/

Keywords: COVID-19; SARS-CoV-2; T cell receptor; fibrosis; inflammation; scRNAseq; Humans; COVID-19; Single-Cell Analysis; SARS-CoV-2; Male; Female; Middle Aged; Receptors, Antigen, T-Cell; Pulmonary Fibrosis; CD8-Positive T-Lymphocytes; CD4-Positive T-Lymphocytes; Lung; Aged; Adult; Inflammation; Bronchoalveolar Lavage Fluid; Memory T Cells; Transcriptome
Dates:
  • Published: 17 May 2024
  • Published (online): 17 May 2024
  • Accepted: 7 May 2024
  • Submitted: 18 January 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Funding Information:
Funder
Grant number
Medical Research Council
MR/N007727/1
Depositing User: Symplectic Sheffield
Date Deposited: 31 Jan 2025 10:49
Last Modified: 31 Jan 2025 10:49
Status: Published
Publisher: Frontiers Media SA
Refereed: Yes
Identification Number: 10.3389/fimmu.2024.1372658
Related URLs:
Sustainable Development Goals:
  • Sustainable Development Goals: Goal 3: Good Health and Well-Being
Open Archives Initiative ID (OAI ID):

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