Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization

Choppakatla, P. orcid.org/0000-0003-0387-913X, Dekker, B., Cutts, E.E. orcid.org/0000-0003-3290-4293 et al. (3 more authors) (2021) Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization. eLife, 10. e68918. ISSN 2050-084X

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Item Type: Article
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© 2021 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: Hi-C; chromatin; chromosome compaction; chromosomes; gene expression; linker histone; mitosis; nucleosome; xenopus; Adenosine Triphosphatases; Animals; Cell Extracts; Chromatin; Chromosomes; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Histones; Models, Biological; Multiprotein Complexes; Oocytes; Spindle Apparatus; Xenopus laevis
Dates:
  • Published: 18 August 2021
  • Published (online): 18 August 2021
  • Accepted: 13 August 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 23 Jan 2025 10:49
Last Modified: 23 Jan 2025 10:49
Published Version: https://doi.org/10.7554/elife.68918
Status: Published
Publisher: eLife Sciences Publications, Ltd
Refereed: Yes
Identification Number: 10.7554/elife.68918
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