Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo

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• Vaizoglu, D.
• Cammack, A.J.
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• Roberts, M.J. https://orcid.org/0009-0003-6441-6865
• Mikheenko, A.
• Fisher, A.
• Suklai, P.
• Muralidharan, B.
• Kroll, F. https://orcid.org/0000-0001-9908-2648
• Moens, T.G.
• Yshii, L.
• Verschoren, S.
• Hölbling, B.V.
• Moreira, F.C. https://orcid.org/0000-0002-7148-4386
• Katona, E.
• Coneys, R.
• de Oliveira, P.
• Zhang, Y.-J.
• Jansen, K.
• Daughrity, L.M. https://orcid.org/0000-0003-4644-7265
• McGown, A.
• Ramesh, T.M. https://orcid.org/0000-0001-8398-5367
• Van Den Bosch, L.
• Lignani, G. https://orcid.org/0000-0002-3963-9296
• Rahim, A.A.
• Coyne, A.N. https://orcid.org/0000-0002-3658-5325
• Petrucelli, L.
• Rihel, J. https://orcid.org/0000-0003-4067-2066
• Isaacs, A.M. https://orcid.org/0000-0002-6820-5534

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• Published: 8 January 2025
• Published (online): 8 January 2025
• Accepted: 11 December 2024
• Submitted: 23 January 2024