Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM

Valerie, N.C.K. orcid.org/0000-0002-9423-964X, Sanjiv, K., Mortusewicz, O. orcid.org/0000-0002-4290-4994 et al. (21 more authors) (2024) Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM. Nature Communications, 15. 10347. ISSN 2041-1723

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Item Type: Article
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© 2024 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: Humans; Animals; Poly(ADP-ribose) Polymerase Inhibitors; Poly (ADP-Ribose) Polymerase-1; Pyrophosphatases; Biosensing Techniques; DNA Repair Enzymes; Mice; Mutation; HEK293 Cells; High-Throughput Screening Assays; Protein Binding
Dates:
  • Published: 6 December 2024
  • Published (online): 6 December 2024
  • Accepted: 11 November 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 10 Jan 2025 16:35
Last Modified: 10 Jan 2025 16:35
Published Version: https://doi.org/10.1038/s41467-024-54415-7
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: 10.1038/s41467-024-54415-7
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Sustainable Development Goals:
  • Sustainable Development Goals: Goal 3: Good Health and Well-Being
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