Smith, R.A. orcid.org/0000-0003-0245-3217, Samyshkin, Y. orcid.org/0000-0003-3561-5585, Mohammed, W. orcid.org/0000-0003-0370-4903 et al. (14 more authors) (2024) assertHE: an R package to improve quality assurance of HTA models [version 1; peer review: 1 approved with reservations]. Wellcome Open Research, 9. 701. ISSN 2398-502X
Abstract
Background Health economic models are increasingly used to inform decisions about the allocation of healthcare resources. Ensuring the robustness and reliability of these models is critical. Currently, quality assurance is conducted by both technical and non-technical experts assessing different components of the model manually. This is resource intensive. Understanding how the different components of the model fit together is time consuming, and testing every part of the model is sometimes not feasible in the time available. To aid in this, we have developed the assertHE R package. Methods The open-source assertHE package provides testing functionality for those building and reviewing health economic models built in R programming language. It provides a series of checks which can be integrated into the model development workflow to reduce the probability of common errors. It also provides a suite of functions which allow users to better understand the network of R functions contained in a model, where they are defined, if (and where) they are tested, and provides a simple metric to quantify the extent to which they are tested. Results We applied the assertHE package to three open-source health economic models built in R, showing how to include check functions within the model code and how to visualise the network of functions, see the test coverage, and obtain a Generative Pretrained Transformer Large Language Model (GPT-LLM) generated summary of any function in the code-base. We have worked with collaborators from industry, regulators and academia to develop the package to be applicable to the widest possible range of models, making adaptations to the source code based upon feedback. Conclusions assertHE offers an open-source toolkit for health economists building and reviewing models, promoting collaborative development and facilitating a more robust and efficient quality assurance process.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2024 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Funding Information: | Funder Grant number Wellcome Trust 108903/B/15/Z |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 16 Jan 2025 16:42 |
Last Modified: | 13 Mar 2025 09:25 |
Published Version: | https://doi.org/10.12688/wellcomeopenres.23180.1 |
Status: | Published |
Publisher: | F1000 Research Ltd |
Identification Number: | 10.12688/wellcomeopenres.23180.1 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:221507 |
Download
Filename: 4edeaca8-52a6-4fb9-82c4-9e84827624c5_23180_-_robert_smith_(2).pdf
Licence: CC-BY 4.0