Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models

Hynds, R.E. orcid.org/0000-0002-2170-8791, Huebner, A. orcid.org/0000-0001-8009-4999, Pearce, D.R. orcid.org/0000-0001-8443-2924 et al. (274 more authors) (2024) Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature Communications, 15 (1). 4653. ISSN 2041-1723

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Item Type: Article
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© The Author(s) 2024. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Keywords: Carcinoma, Non-Small-Cell Lung; Humans; Animals; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Genetic Heterogeneity; Female; Exome Sequencing; Genomics; Male; Xenograft Model Antitumor Assays; Heterografts; Disease Models, Animal; Aged; Middle Aged
Dates:
  • Published: 31 May 2024
  • Published (online): 31 May 2024
  • Accepted: 28 March 2024
  • Submitted: 6 June 2023
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Depositing User: Symplectic Sheffield
Date Deposited: 09 Jan 2025 15:43
Last Modified: 09 Jan 2025 15:43
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: 10.1038/s41467-024-47547-3
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Sustainable Development Goals:
  • Sustainable Development Goals: Goal 3: Good Health and Well-Being
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