Probing the interplay between drug saturation, processing temperature and microstructure of amorphous solid dispersions with synchrotron X-ray phase-contrast tomography

Bordos, E., Das, G., Schroeder, S.L.M. orcid.org/0000-0002-4232-5378 et al. (3 more authors) (2025) Probing the interplay between drug saturation, processing temperature and microstructure of amorphous solid dispersions with synchrotron X-ray phase-contrast tomography. International Journal of Pharmaceutics, 669. 125018. ISSN 0378-5173

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Item Type: Article
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© 2024 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords: Amorphous solid dispersions; Hot-melt extrusion; Low-frequency Raman; X-ray phase-contrast tomography; ASD microstructure; API-polymer solubility
Dates:
  • Published: 25 January 2025
  • Published (online): 4 December 2024
  • Accepted: 29 November 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 08 Jan 2025 16:38
Last Modified: 08 Jan 2025 16:38
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.ijpharm.2024.125018
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