MYO7A is required for the functional integrity of the mechanoelectrical transduction complex in hair cells of the adult cochlea

Underhill, A. orcid.org/0000-0002-6876-861X, Webb, S., Grandi, F.C. orcid.org/0000-0002-1303-6710 et al. (13 more authors) (2025) MYO7A is required for the functional integrity of the mechanoelectrical transduction complex in hair cells of the adult cochlea. Proceedings of the National Academy of Sciences, 122 (1). e2414707122. ISSN 0027-8424

Abstract

Metadata

Item Type: Article
Authors/Creators:
Copyright, Publisher and Additional Information:

© 2025 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: cochlea; hair cell; hearing loss; mechanoelectrical transduction; stereocilia; Myosin VIIa; Animals; Mice; Hair Cells, Auditory; Mechanotransduction, Cellular; Myosins; Cochlea; Mice, Knockout; Hearing; Stereocilia
Dates:
  • Published: 7 January 2025
  • Published (online): 2 January 2025
  • Accepted: 26 November 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 13 Jan 2025 11:19
Last Modified: 13 Jan 2025 11:19
Published Version: https://doi.org/10.1073/pnas.2414707122
Status: Published
Publisher: Proceedings of the National Academy of Sciences
Refereed: Yes
Identification Number: 10.1073/pnas.2414707122
Related URLs:
Open Archives Initiative ID (OAI ID):

Export

Statistics