Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction

Yiangou, K., Mavaddat, N., Dennis, J. et al. (124 more authors) (2024) Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction. Breast Cancer Research, 26. 189. ISSN 1465-5411

Abstract

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Item Type: Article
Authors/Creators:
  • Yiangou, K.
  • Mavaddat, N.
  • Dennis, J.
  • Zanti, M.
  • Wang, Q.
  • Bolla, M.K.
  • Abubakar, M.
  • Ahearn, T.U.
  • Andrulis, I.L.
  • Anton-Culver, H.
  • Antonenkova, N.N.
  • Arndt, V.
  • Aronson, K.J.
  • Augustinsson, A.
  • Baten, A.
  • Behrens, S.
  • Bermisheva, M.
  • de Gonzalez, A.B.
  • Białkowska, K.
  • Boddicker, N.
  • Bodelon, C.
  • Bogdanova, N.V.
  • Bojesen, S.E.
  • Brantley, K.D.
  • Brauch, H.
  • Brenner, H.
  • Camp, N.J.
  • Canzian, F.
  • Castelao, J.E.
  • Cessna, M.H.
  • Chang-Claude, J.
  • Chenevix-Trench, G.
  • Chung, W.K.
  • Colonna, S.V.
  • Couch, F.J.
  • Cox, A.
  • Cross, S.S.
  • Czene, K.
  • Daly, M.B.
  • Devilee, P.
  • Dörk, T.
  • Dunning, A.M.
  • Eccles, D.M.
  • Eliassen, A.H.
  • Engel, C.
  • Eriksson, M.
  • Evans, D.G.
  • Fasching, P.A.
  • Fletcher, O.
  • Flyger, H.
  • Fritschi, L.
  • Gago-Dominguez, M.
  • Gentry-Maharaj, A.
  • González-Neira, A.
  • Guénel, P.
  • Hahnen, E.
  • Haiman, C.A.
  • Hamann, U.
  • Hartikainen, J.M.
  • Ho, V.
  • Hodge, J.
  • Hollestelle, A.
  • Honisch, E.
  • Hooning, M.J.
  • Hoppe, R.
  • Hopper, J.L.
  • Howell, S.
  • Howell, A.
  • Jakovchevska, S.
  • Jakubowska, A.
  • Jernström, H.
  • Johnson, N.
  • Kaaks, R.
  • Khusnutdinova, E.K.
  • Kitahara, C.M.
  • Koutros, S.
  • Kristensen, V.N.
  • Lacey, J.V.
  • Lambrechts, D.
  • Lejbkowicz, F.
  • Lindblom, A.
  • Lush, M.
  • Mannermaa, A.
  • Mavroudis, D.
  • Menon, U.
  • Murphy, R.A.
  • Nevanlinna, H.
  • Obi, N.
  • Offit, K.
  • Park-Simon, T.-W.
  • Patel, A.V.
  • Peng, C.
  • Peterlongo, P.
  • Pita, G.
  • Plaseska-Karanfilska, D.
  • Pylkäs, K.
  • Radice, P.
  • Rashid, M.U.
  • Rennert, G.
  • Roberts, E.
  • Rodriguez, J.
  • Romero, A.
  • Rosenberg, E.H.
  • Saloustros, E.
  • Sandler, D.P.
  • Sawyer, E.J.
  • Schmutzler, R.K.
  • Scott, C.G.
  • Shu, X.-O.
  • Southey, M.C.
  • Stone, J.
  • Taylor, J.A.
  • Teras, L.R.
  • van de Beek, I.
  • Willett, W.
  • Winqvist, R.
  • Zheng, W.
  • Vachon, C.M.
  • Schmidt, M.K.
  • Hall, P.
  • MacInnis, R.J.
  • Milne, R.L.
  • Pharoah, P.D.P.
  • Simard, J.
  • Antoniou, A.C.
  • Easton, D.F.
  • Michailidou, K.
Copyright, Publisher and Additional Information:

© 2024 The Authors. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Keywords: Breast cancer; Polygenic risk scores; Risk calibration; Risk prediction; Humans; Female; Breast Neoplasms; Genetic Predisposition to Disease; Multifactorial Inheritance; White People; Risk Assessment; Risk Factors; Europe; Polymorphism, Single Nucleotide; Genome-Wide Association Study; Middle Aged; Genotype
Dates:
  • Published: 29 December 2024
  • Published (online): 29 December 2024
  • Accepted: 9 December 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Oncology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 03 Jan 2025 16:25
Last Modified: 03 Jan 2025 16:25
Published Version: https://doi.org/10.1186/s13058-024-01947-x
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: 10.1186/s13058-024-01947-x
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Open Archives Initiative ID (OAI ID):

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