Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC‐derived astrocytes

Elsworthy, R.J. orcid.org/0000-0002-8504-9801, Finelli, M.J., Aqattan, S. et al. (13 more authors) (2025) Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC‐derived astrocytes. Journal of Neurochemistry, 169 (1). e16267. ISSN 0022-3042

Abstract

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Item Type: Article
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© 2024 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: Alzheimer's; astrocytes; gliosis; inflammation; metabolism; stem cells; Astrocytes; Humans; Induced Pluripotent Stem Cells; Amyloid beta-Peptides; Presenilin-1; Alzheimer Disease; Mutation; Cells, Cultured; Female; Cell Differentiation; Male; Peptide Fragments
Dates:
  • Published: January 2025
  • Published (online): 18 December 2024
  • Accepted: 1 November 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 03 Jan 2025 16:44
Last Modified: 03 Jan 2025 16:44
Published Version: https://doi.org/10.1111/jnc.16267
Status: Published
Publisher: Wiley
Refereed: Yes
Identification Number: 10.1111/jnc.16267
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