Saldivia, Manuel, Lima, Ana Paula C A and Mottram, Jeremy C orcid.org/0000-0001-5574-3766 (2024) A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas' disease. Trends in parasitology. pp. 211-213. ISSN 1471-4922
Abstract
The drug discovery pipeline for leishmaniasis and trypanosomiasis has been filling with novel chemical entities with known mechanisms of action. González et al. and Braillard et al. report a cytochrome bc1 complex inhibitor as another promising preclinical candidate for visceral leishmaniasis (VL) and, in combination with benznidazole, for chronic Chagas' disease (CCD).
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. |
Keywords: | Humans,Chagas Disease/drug therapy,Leishmaniasis/drug therapy,Trypanosomiasis,Leishmaniasis, Visceral/drug therapy,Trypanosoma cruzi |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Biology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 20 Dec 2024 15:00 |
Last Modified: | 21 Dec 2024 00:26 |
Published Version: | https://doi.org/10.1016/j.pt.2024.02.002 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.pt.2024.02.002 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:221079 |
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Description: A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas’ disease
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