Matza, L., Howell, T.A., Chun, B. et al. (11 more authors) (2025) Health state utilities associated with invasive pneumococcal disease, pneumonia, and recurrent acute otitis media in young children. Quality of Life Research. ISSN 0962-9343
Abstract
As new vaccines for pneumococcal disease are considered for use in young children, cost-effectiveness analyses will be needed to examine their value and inform decisions about healthcare funding. Utilities, which are values representing the strength of preference for health states, are needed to quantify health outcomes and health-related quality of life in these analyses. In the current study, utilities were estimated for several pneumococcal infections that are common in children younger than 5 years old. These utilities will be useful in analyses examining the value of pneumococcal vaccines. This study also makes a broader contribution to research on pediatric utility assessment. By piloting several utility assessment methods, the current study identified an effective approach for eliciting utilities associated with temporary medical conditions in children younger than 5 years old. These findings have methodological implications for future research estimating utilities associated with temporary pediatric health conditions.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2025 The Authors. Except as otherwise noted, this author-accepted version of a journal article published in Quality of Life Research is made available via the University of Sheffield Research Publications and Copyright Policy under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ © 2025 Merck & Co., Inc., Rahway, NJ, USA and its affliates & Imperial College London & Louis S. Matza, Timothy A. Howell, Lucinda Hetherington, Donna Rowen, Tina Tan, Matthew S. Kelly, Alejandro Hoberman. This article is licensed under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. |
Keywords: | Health state utilities; children; pediatric; time trade-off; cost-effectiveness; pneumococcal infections; streptococcus pneumoniae |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 19 Dec 2024 09:15 |
Last Modified: | 07 Jan 2025 14:15 |
Status: | Published online |
Publisher: | Springer |
Refereed: | Yes |
Identification Number: | 10.1007/s11136-024-03840-8 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:220898 |
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Filename: EVA-31206_Revised Manuscript for QLR_18Nov2024_Clean ACCEPTED (1).pdf
Licence: CC-BY 4.0
Filename: s11136-024-03840-8.pdf
Licence: CC-BY-NC-ND 4.0