Shiha, M.G. orcid.org/0000-0002-2713-8355, Bowker-Howell, F.J. orcid.org/0000-0003-3331-9934, Harper, A.M. et al. (4 more authors) (2025) Exploring the views of primary and secondary care physicians on the no-biopsy diagnosis of coeliac disease in adults: a qualitative interview study. Frontline Gastroenterology, 16 (2). pp. 101-107. ISSN 2041-4137
Abstract
Objective: Despite mounting evidence supporting a no-biopsy approach for the diagnosis of coeliac disease in adults, established clinical pathways in primary and secondary care could hinder implementation in clinical practice. We aimed to identify the barriers and facilitators to a no-biopsy diagnostic pathway of coeliac disease in primary and secondary care.
Methods: We conducted a qualitative study using semistructured interviews with gastroenterologists and general practitioners (GPs). We used a predefined interview topic guide consisting of open-ended questions and prompts to facilitate discussion about the views of primary and secondary care physicians on the no-biopsy diagnosis of coeliac disease in adults.
Results: We interviewed 24 physicians (12 gastroenterologists and 12 GPs) across England between February and March 2024. Participants had different levels of experience ranging between 2 years and 30 years. Gastroenterologists were more familiar with the no-biopsy approach and the evidence supporting it compared with GPs. Both groups were supportive of the no-biopsy approach but acknowledged the lack of clear guidelines as a major barrier to implementation in clinical practice. Increased patient satisfaction, shorter waiting times to start treatment and reduced endoscopy service pressures and costs were perceived as the main advantages of the no-biopsy approach. However, participants had concerns regarding false-positive results, missing concurrent pathology, dealing with persistent symptoms after treatment without biopsy confirmation and the increased workload in primary care.
Conclusion: The safe and effective implementation of this no-biopsy approach depends on developing clear evidence-based clinical guidelines and referral pathways, along with comprehensive education for all healthcare providers involved.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
Keywords: | Biomedical and Clinical Sciences; Clinical Sciences; Individual care needs |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection, Immunity and Cardiovascular Disease |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Dec 2024 16:06 |
Last Modified: | 12 Mar 2025 17:21 |
Status: | Published |
Publisher: | BMJ |
Refereed: | Yes |
Identification Number: | 10.1136/flgastro-2024-102837 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:220381 |