Benemerito, I. orcid.org/0000-0002-4942-7852, Melis, A. orcid.org/0000-0002-8261-0421, Wehenkel, A. orcid.org/0000-0001-5022-3999 et al. (1 more author) (2024) openBF: an open-source finite volume 1D blood flow solver. Physiological Measurement, 45. 125002. ISSN 0967-3334
Abstract
Computational simulations are widely adopted in cardiovascular biomechanics because of their capability of producing physiological data otherwise impossible to measure with non-invasive modalities. Objective. This study presents openBF, a computational library for simulating the blood dynamics in the cardiovascular system. Approach. openBF adopts a one-dimensional viscoelastic representation of the arterial system, and is coupled with zero-dimensional windkessel models at the outlets. Equations are solved by means of the finite-volume method and the code is written in Julia. We assess its predictions by performing a multiscale validation study on several domains available from the literature. Main results. At all scales, which range from individual arteries to a population of virtual subjects, openBF's solution show excellent agreement with the solutions from existing software. For reported simulations, openBF requires low computational times. Significance. openBF is easy to install, use, and deploy on multiple platforms and architectures, and gives accurate prediction of blood dynamics in short time-frames. It is actively maintained and available open-source on GitHub, which favours contributions from the biomechanical community.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 The Author(s). Published on behalf of Institute of Physics and Engineering in Medicine by IOP Publishing Ltd. Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 license (https://creativecommons.org/licenses/by/4.0/). Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. |
Keywords: | 1D modelling; cardiovascular system; open source; validation |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > School of Mechanical, Aerospace and Civil Engineering |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Dec 2024 14:43 |
Last Modified: | 13 Dec 2024 14:43 |
Status: | Published |
Publisher: | IOP Publishing |
Refereed: | Yes |
Identification Number: | 10.1088/1361-6579/ad9663 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:220365 |
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