Heightened mitochondrial respiration in CF cells is normalised by triple CFTR modulator therapy through mechanisms involving calcium

Jarosz-Griffiths, H.H. orcid.org/0000-0001-5154-4815, Caley, L.R. orcid.org/0000-0001-8957-1018, Lara-Reyna, S. et al. (4 more authors) (2024) Heightened mitochondrial respiration in CF cells is normalised by triple CFTR modulator therapy through mechanisms involving calcium. Heliyon, 10 (20). e39244. ISSN 1879-4378

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Item Type: Article
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© 2024 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Keywords: Cystic fibrosis; Metabolism; Elexacaftor/tezacaftor/ivacaftor; Mitochondrial reactive oxygen species; Mitochondria; CFTR; Calcium
Dates:
  • Published: 30 October 2024
  • Published (online): 11 October 2024
  • Accepted: 10 October 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Medical Research (LIMR) > Division of Molecular Medicine
The University of Leeds > Faculty of Biological Sciences (Leeds) > Faculty of Biological Sciences Office (Leeds)
?? Leeds.RC-HURS ??
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Inflammatory Arthritis (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 02 Dec 2024 17:16
Last Modified: 02 Dec 2024 17:16
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.heliyon.2024.e39244
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