Taher, M.M.B. orcid.org/0009-0000-7716-5477, Skerry, T.M., Cohen, M.C. et al. (2 more authors) (2024) Correlation of CT measurements of total body gas volume and hounsfield units with post-mortem interval. Indian Journal of Forensic and Community Medicine, 11 (3). pp. 111-118. ISSN 2394-6768
Abstract
Background: Accurate estimation of the post-mortem interval (PMI) may be a matter of crucial importance in forensic investigations. A preliminary investigation to assess whether longitudinal changes in organ Hounsfield units (HU) and total body gas volume (TBGV), as measured from serial PMCT scans, correlate with postmortem interval (PMI). Materials and Methods: Eight euthanised lambs each had five whole body CT scans performed over seven days and measurements were taken from the brain, heart, lungs, liver, kidneys and spleen. HU tissue density was measured directly from the PMCT images, while TBGV was calculated using ImageJ software. A random effect model was fitted with the subject fitted as a random intercept. Ethical and Animal Welfare approval was obtained. Results: The average increase in TBGV was 422 ml/Kg with a change of 77 ml/Kg per day. For each additional post-mortem day, the HU of the brain, heart, lung, liver and spleen decreased by per day since death, while HU for the kidneys increased by day since death. Conclusion: Expect for the kidney where it increased, there was clear and progressive decrease in tissue densities and for all organs there was an increase in TBGV over time. However, the overlap in values between cases indicates that more work is required before either HU or TBGV can be developed as non-invasive methods to reliably determine time of death in humans.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Post- mortem interval (PMI); Hounsfield units (HU); Computed tomography (PMCT); Total body gas volume (TBGV) |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 12 Nov 2024 14:17 |
Last Modified: | 14 Jan 2025 20:06 |
Published Version: | http://dx.doi.org/10.18231/j.ijfcm.2024.025 |
Status: | Published |
Publisher: | IP Innovative Publication Pvt Ltd |
Refereed: | Yes |
Identification Number: | 10.18231/j.ijfcm.2024.025 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:219442 |
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