Relationships of brain cholesterol and cholesterol biosynthetic enzymes to Alzheimer’s pathology and dementia in the CFAS population-derived neuropathology cohort

Mistry, H., Richardson, C.D., Higginbottom, A. orcid.org/0000-0002-3246-6695 et al. (7 more authors) (2024) Relationships of brain cholesterol and cholesterol biosynthetic enzymes to Alzheimer’s pathology and dementia in the CFAS population-derived neuropathology cohort. Neuroscience Research, 204. pp. 22-33. ISSN 0168-0102

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Item Type: Article
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© 2024 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Keywords: Alzheimer’s disease; Cholesterol; Cognitive Function and Ageing Study; Dementia; HMG-CoA reductase; Sterol regulatory element-binding proteins; Humans; Cholesterol; Male; Sterol Regulatory Element Binding Protein 2; Hydroxymethylglutaryl CoA Reductases; Female; Alzheimer Disease; Aged; Dementia; Aged, 80 and over; Brain; Cohort Studies; Neurons; Cholesterol 24-Hydroxylase; Astrocytes
Dates:
  • Published: July 2024
  • Published (online): 24 January 2024
  • Accepted: 17 January 2024
  • Submitted: 1 June 2023
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Funding Information:
Funder
Grant number
Medical Research Council
G0900582
Medical Research Council
G9901400
MEDICAL RESEARCH COUNCIL
G0900582/1
Depositing User: Symplectic Sheffield
Date Deposited: 01 Nov 2024 10:00
Last Modified: 01 Nov 2024 10:00
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.neures.2024.01.003
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