Phillips, Bob orcid.org/0000-0002-4938-9673, Morgan, Jess, Walker, Ruth orcid.org/0000-0003-2765-7363 et al. (2 more authors) (2024) Interventions to reduce the risk of side-effects of cancer treatments in childhood. Expert review of anticancer therapy. pp. 1117-1129. ISSN 1744-8328
Abstract
INTRODUCTION: Childhood cancers as a group affect around 1 in 500 children but each individual diagnosis is a rare disease. While research largely focuses on improving cure rates, the management of side effects of treatment are high priority for clinicians, families and children and young people. AREAS COVERED: The prevention and efficient management of infectious complications, oral mucositis, nausea and vomiting and graft-vs-host disease illustrated with examples of implementation research, translation of engineering to care, advances in statistical methodologies, and traditional bench-to-patient development. The reviews draw from existing systematic reviews and well conducted clinical practice guidelines. EXPERT OPINION: The four areas are driven from patient and family priorities. Some of the problems outlined are ready for proven interventions, others require us to develop new technologies. Advancement needs us to make the best use of new methods of applied health research and clinical trial methodologies. Some of the greatest challenges may be those we're not fully aware of, as new therapies move from their use in adult oncological practice into children. This will need us to continue our collaborative, multi-professional, multi-disciplinary and eclectic approach.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 The Author(s) |
Keywords: | Humans,Neoplasms/drug therapy,Child,Antineoplastic Agents/adverse effects,Practice Guidelines as Topic,Risk |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Social Sciences (York) > Centre for Reviews and Dissemination (York) The University of York > Faculty of Sciences (York) > Hull York Medical School (York) The University of York > Faculty of Sciences (York) > Health Sciences (York) |
Depositing User: | Pure (York) |
Date Deposited: | 29 Oct 2024 11:30 |
Last Modified: | 30 Oct 2024 01:08 |
Published Version: | https://doi.org/10.1080/14737140.2024.2411255 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1080/14737140.2024.2411255 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:218972 |
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Description: Interventions to reduce the risk of side-effects of cancer treatments in childhood
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