Salum, Thaís Fabiana Chan, Day, Daniel, Sherwood, James orcid.org/0000-0001-5431-2032 et al. (2 more authors) (2024) Enzymatic synthesis of aromatic biobased polymers in green, low-boiling solvents. Journal of biotechnology. pp. 1-9. ISSN 0168-1656
Abstract
Given the urge to accelerate the substitution of petrol-derived solvents not only in more traditional fields like pharmaceuticals, personal care, or electronics but also in innovative research processes, this work focuses on the utilisation of four biobased solvents as media for the enzymatic synthesis of aliphatic-aromatic polyesters. As building blocks, the lignin-derived diethyl-2,4-pyridinedicarboxylate was selected as the potentially biobased, aromatic component while more classical diols such as 1,4-butanediol and 1,8-octanediol were used as the aliphatic portion. Results show that among the tested green solvents (cyclohexanone, phenetole, anisole and eucalyptol), the most suitable medium for lipase B from Candida antarctica-catalysed polycondensation reactions was eucalyptol that allowed reach monomer conversions >95% and number average molecular weights up to 3500g·mol -1. On the other hand, cyclohexanone led to the lowest monomer conversions (<80%) and molecular weights (M n<500g·mol -1) confirmi ng once again the unsuitability of ketone-containing solvents for enzymatic esterification and transesterification reactions. The lipase could be used up to three times, in eucalyptol as a solvent, without a significant decrease in monomer conversion or molecular weight.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 18 Oct 2024 12:00 |
Last Modified: | 02 Apr 2025 23:28 |
Published Version: | https://doi.org/10.1016/j.jbiotec.2024.10.003 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.jbiotec.2024.10.003 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:218593 |
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Description: Enzymatic synthesis of aromatic biobased polymers in green, low-boiling solvents
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