Rajeswaran, T., Gojsevic, M., Chan, A.W. et al. (20 more authors) (2024) Quality of life issues in patients with ductal carcinoma in situ: a systematic review. Supportive Care in Cancer, 32 (695). ISSN 0941-4355
Abstract
Purpose Ductal carcinoma in situ (DCIS) of the breast is one of the most common pre-invasive cancers diagnosed in women. Quality of life (QoL) is extremely important to assess in studies including these patients due to the favorable prognosis of the disease. The primary objective of this systematic review was to compile a comprehensive list of QoL issues, all existing QoL assessment tools, and patient-reported outcome measures used to assess DCIS.
Methods A search was conducted on Ovid MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases from inception to August 2023, using keywords such as “ductal carcinoma in-situ”, “quality of life”, and “patient-reported outcomes.” QoL issues and QoL tools in primary research studies were extracted.
Results A total of 67 articles identified issues pertaining to patients with DCIS spanning physical, functional, and psychosocial QoL domains. Physical and functional issues observed in patients included pain, fatigue, and impaired sexual functioning. Psychosocial issues such as anxiety, depression, and confusion about one’s disease were also common. QoL tools included those that assessed general QoL, breast cancer-specific tools, and issue-specific questionnaires.
Conclusion The current instruments available to assess QoL in patients with DCIS do not comprehensively capture the issues that are pertinent to patients. Thus, the modification of existing tools or the creation of a DCIS-specific QoL tool is recommended to ensure that future research will be sensitive towards challenges faced by patients with DCIS.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | This is an author produced version of an article accepted for publication in Supportive Care in Cancer, made available under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Ductal carcinoma in situ; Quality of life; Patient-reported outcome; Pre-invasive cancer; Breast; Systematic review |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Medical Research (LIMR) > Division of Oncology |
Depositing User: | Symplectic Publications |
Date Deposited: | 17 Oct 2024 12:21 |
Last Modified: | 17 Oct 2024 12:21 |
Status: | Published |
Publisher: | Springer Nature |
Identification Number: | 10.1007/s00520-024-08864-x |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:218477 |
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