Conteduca, Donato, Brunetti, Giuseppe, Barth, Isabel et al. (3 more authors) (2023) Multiplexed Near-Field Optical Trapping Exploiting Anapole States. ACS Nano. pp. 16695-16702. ISSN 1936-0851
Abstract
Optical tweezers have had a major impact on bioscience research by enabling the study of biological particles with high accuracy. The focus so far has been on trapping individual particles, ranging from the cellular to the molecular level. However, biology is intrinsically heterogeneous; therefore, access to variations within the same population and species is necessary for the rigorous understanding of a biological system. Optical tweezers have demonstrated the ability of trapping multiple targets in parallel; however, the multiplexing capability becomes a challenge when moving toward the nanoscale. Here, we experimentally demonstrate a resonant metasurface that is capable of trapping a high number of nanoparticles in parallel, thereby opening up the field to large-scale multiplexed optical trapping. The unit cell of the metasurface supports an anapole state that generates a strong field enhancement for low-power near-field trapping; importantly, the anapole state is also more angle-tolerant than comparable resonant modes, which allows its excitation with a focused light beam, necessary for generating the required power density and optical forces. We use the anapole state to demonstrate the trapping of 100’s of 100 nm polystyrene beads over a 10 min period, as well as the multiplexed trapping of lipid vesicles with a moderate intensity of <250 μW/μm2. This demonstration will enable studies relating to the heterogeneity of biological systems, such as viruses, extracellular vesicles, and other bioparticles at the nanoscale.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 The Authors |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
Depositing User: | Pure (York) |
Date Deposited: | 11 Oct 2024 23:23 |
Last Modified: | 24 Oct 2024 00:22 |
Published Version: | https://doi.org/10.1021/acsnano.3c03100 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1021/acsnano.3c03100 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:218330 |
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