Increasing hexokinase 1 expression improves mitochondrial and glycolytic functional deficits seen in sporadic Alzheimer’s disease astrocytes

Bell, S.M. orcid.org/0000-0002-2781-6478, Wareing, H. orcid.org/0000-0003-0785-4116, Capriglia, F. orcid.org/0000-0001-7113-1276 et al. (14 more authors) (2025) Increasing hexokinase 1 expression improves mitochondrial and glycolytic functional deficits seen in sporadic Alzheimer’s disease astrocytes. Molecular Psychiatry, 30 (4). pp. 1369-1382. ISSN 1359-4184

Abstract

Metadata

Item Type: Article
Authors/Creators:
Copyright, Publisher and Additional Information:

© The Author(s) 2024. Open Access: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Keywords: Biochemistry; Molecular biology; Neuroscience
Dates:
  • Published: April 2025
  • Published (online): 13 September 2024
  • Accepted: 3 September 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Funding Information:
Funder
Grant number
EUROPEAN COMMISSION - FP6/FP7
VPH DARE - 601055
ALZHEIMER'S RESEARCH UK
ARUK-PCRF2016A-1
PARKINSONS UK
F-1301
ACADEMY OF MEDICAL SCIENCES
SGL028\1097
National Institute for Health and Care Research
NIHR203321
Depositing User: Symplectic Sheffield
Date Deposited: 16 Oct 2024 09:38
Last Modified: 24 Mar 2025 13:22
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: 10.1038/s41380-024-02746-8
Related URLs:
Open Archives Initiative ID (OAI ID):

Export

Statistics