Ma, C.Y. orcid.org/0000-0002-4576-7411, Jiang, C., Ilett, T.P. et al. (3 more authors) (2024) Deconstructing 3D growth rates from transmission microscopy images of facetted crystals as captured in situ within supersaturated aqueous solutions. Journal of Applied Crystallography, 57 (5). pp. 1557-1565. ISSN 0021-8898
Abstract
Here, a morphologically based approach is used for the in situ characterization of 3D growth rates of facetted crystals from the solution phase. Crystal images of single crystals of the β-form of L-glutamic acid are captured in situ during their growth at a relative supersaturation of 1.05 using transmission optical microscopy. The crystal growth rates estimated for both the {101} capping and {021} prismatic faces through image processing are consistent with those determined using reflection light mode [Jiang, Ma, Hazlehurst, Ilett, Jackson, Hogg & Roberts (2024[Jiang, C., Ma, C. Y., Hazlehurst, T. A., Ilett, T. P., Jackson, A. S. M., Hogg, D. C. & Roberts, K. J. (2024). Cryst. Growth Des. 24, 3277-3288.]). Cryst. Growth Des. 24, 3277–3288]. The growth rate in the {010} face is, for the first time, estimated from the shadow widths of the {021} prismatic faces and found to be typically about half that of the {021} prismatic faces. Analysis of the 3D shape during growth reveals that the initial needle-like crystal morphology develops during the growth process to become more tabular, associated with the Zingg factor evolving from 2.9 to 1.7 (>1). The change in relative solution supersaturation during the growth process is estimated from calculations of the crystal volume, offering an alternative approach to determine this dynamically from visual observations.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | This item is protected by copyright. This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
Keywords: | L-glutamic acid; crystal morphological images; facet-based crystal-growth-rate measurements; polyhedral image analysis; 3D crystal growth evolution; in situ characterization; transmission microscopy; supersaturation |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds) |
Funding Information: | Funder Grant number EPSRC (Engineering and Physical Sciences Research Council) EP/W003678/1 |
Depositing User: | Symplectic Publications |
Date Deposited: | 02 Oct 2024 15:17 |
Last Modified: | 02 Oct 2024 15:17 |
Status: | Published |
Publisher: | International Union of Crystallography |
Identification Number: | 10.1107/S1600576724008173 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:217695 |