In vitro and in vivo studies on a mononuclear ruthenium complex reveals it is a highly effective, fast-acting, broad-spectrum antimicrobial in physiologically relevant conditions

Varney, A.M. orcid.org/0000-0002-5943-161X, Smitten, K.L., Southam, H.M. et al. (4 more authors) (2024) In vitro and in vivo studies on a mononuclear ruthenium complex reveals it is a highly effective, fast-acting, broad-spectrum antimicrobial in physiologically relevant conditions. ACS Infectious Diseases, 10 (9). pp. 3346-3357. ISSN 2373-8227

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Item Type: Article
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© 2024 The Authors. This publication is licensed under CC-BY 4.0 - https://creativecommons.org/licenses/by/4.0/

Keywords: AMR; ESKAPE; Galleria; combinatorial therapy; ruthenium; Animals; Anti-Bacterial Agents; Microbial Sensitivity Tests; Ruthenium; Moths; Staphylococcus aureus; Humans; Urinary Tract Infections; Coordination Complexes; Staphylococcal Infections
Dates:
  • Published: 13 September 2024
  • Published (online): 6 August 2024
  • Accepted: 25 July 2024
  • Submitted: 31 May 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Mathematical and Physical Sciences
Depositing User: Symplectic Sheffield
Date Deposited: 23 Sep 2024 14:44
Last Modified: 23 Sep 2024 14:44
Status: Published
Publisher: American Chemical Society (ACS)
Refereed: Yes
Identification Number: 10.1021/acsinfecdis.4c00447
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