Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer

Rosendahl Huber, A., Pleguezuelos-Manzano, C., Puschhof, J. et al. (14 more authors) (2024) Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer. Cancer Cell, 42 (3). 487-496.e6. ISSN 1535-6108

Abstract

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Item Type: Article
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© 2024 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Keywords: cancer genomics; genotoxins; organoids; mutational signatures; colorectal cancer; colibactin; probiotics; bacteria; mutagenesis; machine learning
Dates:
  • Published: 11 March 2024
  • Published (online): 11 March 2024
  • Accepted: 14 February 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Medical Research (LIMR) > Division of Pathology and Data Analytics
Funding Information:
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Grant number
Cancer Research UK Supplier No: 138573
A29067
Depositing User: Symplectic Publications
Date Deposited: 16 Sep 2024 15:49
Last Modified: 16 Sep 2024 15:49
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.ccell.2024.02.009
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