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Quintero-Martinez, J.A., Hindy, J.-R., Villarraga, H.R. et al. (9 more authors) (2024) Echocardiographic findings and subsequent risk of native valve endocarditis. Exploration of Cardiology, 2 (5). pp. 204-216. ISSN 2994-5526
Abstract
Aim: The association of echocardiographic findings and subsequent risk of left-sided native valve endocarditis (LS-NVE) is undefined. The aim of this study was to determine if transthoracic echocardiography (TTE) measurements are associated with the subsequent development of LS-NVE in patients without cardiac predisposing conditions.
Methods: Institutional databases were evaluated for adults diagnosed with LS-NVE from 2008 to 2020. Patients with prosthetic valves, cardiovascular implantable electronic devices, intracardiac devices, injection drug use, and predisposing cardiac conditions were excluded. Only patients who had a TTE performed 6 months to 3 years before the development of LS-NVE were included as cases. Controls were patients within the same Mayo location with a TTE report and were matched in a 1:3 ratio according to age, gender, Charlson comorbidity index, and echocardiography date.
Results: There were 148 cases and 431 matched controls. As compared to controls, infective endocarditis (IE) cases had a higher prevalence of diabetes mellitus (46.6% vs. 30.4%) and chronic kidney disease (46.6% vs. 28.1%) (P < 0.001). Left ventricular outflow tract velocity (P = 0.017), left ventricular ejection fraction (P = 0.018), and E:e’ ratio (P = 0.050) were associated with LS-NVE.
Conclusions: Echocardiographic measurements were associated with subsequent LS-NVE development in this pilot study. A larger cohort of LS-NVE patients, however, is needed to validate these findings.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2024. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
Keywords: | Endocarditis; echocardiography; native valve; left-sided; measurements; risk |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 11 Sep 2024 15:12 |
Last Modified: | 10 Oct 2024 16:17 |
Status: | Published |
Publisher: | Open Exploration Publishing Inc |
Refereed: | Yes |
Identification Number: | 10.37349/ec.2024.00034 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:216941 |
Available Versions of this Item
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Echocardiographic findings and subsequent risk of native valve endocarditis. (deposited 27 Mar 2024 10:53)
- Echocardiographic findings and subsequent risk of native valve endocarditis. (deposited 11 Sep 2024 15:12) [Currently Displayed]