The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence

Osman, Morwan M, Shanahan, Jonathan K, Chu, Frances et al. (6 more authors) (2022) The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence. Proceedings of the National Academy of Sciences of the United States of America. e2122161119. ISSN 1091-6490

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Osman, Morwan M (morwan.osman@york.ac.uk)
  • Shanahan, Jonathan K
  • Chu, Frances
  • Takaki, Kevin K
  • Pinckert, Malte L
  • Pagán, Antonio J
  • Brosch, Roland
  • Conrad, William H
  • Ramakrishnan, Lalita
Keywords: Antigens, Bacterial/chemistry,Bacterial Proteins/chemistry,Humans,Mycobacterium marinum/metabolism,Mycobacterium tuberculosis/metabolism,Phagosomes/metabolism,Protein Conformation,Tuberculoma/microbiology,Type VII Secretion Systems/metabolism,Virulence
Dates:
  • Published: 10 March 2022
  • Accepted: 15 January 2022
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Chemistry (York)
Depositing User: Pure (York)
Date Deposited: 03 Sep 2024 14:00
Last Modified: 16 Oct 2024 20:07
Published Version: https://doi.org/10.1073/pnas.2122161119
Status: Published
Refereed: Yes
Identification Number: 10.1073/pnas.2122161119
Open Archives Initiative ID (OAI ID):

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