Differences in 5'untranslated regions highlight the importance of translational regulation of dosage sensitive genes

Wieder, N., D’Souza, E.N., Martin-Geary, A.C. et al. (10 more authors) (2024) Differences in 5'untranslated regions highlight the importance of translational regulation of dosage sensitive genes. Genome Biology, 25. 111. ISSN 1474-760X

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Wieder, N.
  • D’Souza, E.N.
  • Martin-Geary, A.C.
  • Lassen, F.H.
  • Talbot-Martin, J.
  • Fernandes, M.
  • Chothani, S.P.
  • Rackham, O.J.L.
  • Schafer, S.
  • Aspden, J.L. ORCID logo https://orcid.org/0000-0002-8537-6204
  • MacArthur, D.G.
  • Davies, R.W.
  • Whiffin, N.
Copyright, Publisher and Additional Information:

© The Author(s) 2024. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords: 5’ untranslated regions, 5’UTR, Translational regulation, Upstream open reading frame, uORF, Dosage sensitivity, Loss-of-function
Dates:
  • Published (online): 29 April 2024
  • Accepted: 15 April 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 29 Aug 2024 08:47
Last Modified: 09 Dec 2024 09:27
Status: Published online
Publisher: BMC
Identification Number: 10.1186/s13059-024-03248-0
Related URLs:
Open Archives Initiative ID (OAI ID):

Export

Statistics