Analytical and computational studies predict negligible risk of cell death from eddy generation off flat surfaces in cell culture flow systems

Morley, E.J., Brockett, C.L. orcid.org/0000-0002-6664-7259 and Verbruggen, S.W. (2024) Analytical and computational studies predict negligible risk of cell death from eddy generation off flat surfaces in cell culture flow systems. Frontiers in Bioengineering and Biotechnology, 12. 1340653. ISSN 2296-4185

Abstract

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Item Type: Article
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© 2024 Morley, Brockett and Verbruggen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. http://creativecommons.org/licenses/by/4.0/

Keywords: cell culture therapy; fluid shear stress; eddy formation; microfluidics; T cell bioreactor; Reynolds number
Dates:
  • Published: 7 August 2024
  • Published (online): 7 August 2024
  • Accepted: 24 July 2024
  • Submitted: 18 November 2023
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Mechanical Engineering (Sheffield)
Funding Information:
Funder
Grant number
European Commission
748305
Depositing User: Symplectic Sheffield
Date Deposited: 29 Aug 2024 11:17
Last Modified: 29 Aug 2024 11:17
Status: Published
Publisher: Frontiers Media SA
Refereed: Yes
Identification Number: 10.3389/fbioe.2024.1340653
Open Archives Initiative ID (OAI ID):

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