Hen, O., Harrison, S.R., De Marco, G. orcid.org/0000-0003-2406-161X et al. (1 more author) (Cover date: January-December 2024) Early psoriatic arthritis: when is the right time to start advanced therapy? Therapeutic Advances in Musculoskeletal Disease, 16. ISSN 1759-720X
Abstract
Despite significant advances in the treatment of psoriatic arthritis (PsA) in the last two decades, remission remains elusive and there is no cure. Evidence from rheumatoid arthritis (RA) confirming enhanced response and outcome from earlier treatment intervention suggests the plausibility of the window of opportunity in the pathogenesis of RA. Yet, data are lacking in PsA. Although treatment response may be enhanced in shorter disease duration, it is unknown how this early intervention may impact long-term outcomes. Furthermore, it remains to be demonstrated whether there is a best treatment strategy and time of intervention. Crucially, the main hurdle when aiming for early treatment intervention is the ability to achieve a timely diagnosis that highlights the need to focus research efforts on characterizing the very early disease stages including the transition to PsA in the at-risk psoriasis population.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © The Author(s), 2024. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (CC-BY-NC 4.0). |
Keywords: | advanced therapy, early psoriatic arthritis, treatment strategy |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Musculoskeletal Disease (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 22 Aug 2024 10:11 |
Last Modified: | 04 Dec 2024 16:12 |
Status: | Published |
Publisher: | SAGE Publications |
Identification Number: | 10.1177/1759720x241266727 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:216345 |
Download
Filename: hen-et-al-2024-early-psoriatic-arthritis-when-is-the-right-time-to-start-advanced-therapy.pdf
Licence: CC-BY-NC 4.0