Hofmair, Christopher, Bhakhri, Kunal and Chauhan, Manish orcid.org/0000-0001-9742-5352 (2024) Design and optimisation of soft robotic actuators for augmented lung-ventilation. Biomimetic Intelligence and Robotics. 100172. ISSN 2667-3797
Abstract
Pulmonary rehabilitation through invasive ventilation involves the insertion of an endotracheal tube into the trachea of a sedated patient to control breathing via a ventilating machine. Invasive ventilation offers benefits such as greater control over oxygen supply, higher efficiency in supporting patient respiration, and the ability to manage airway secretions. However, this method also poses treatment challenges like ventilator-induced pneumonia, airway injury, long recovery times, and ventilator dependence. Here, we explore an alternative invasive ventilation technique using soft robotic actuators to mimic the biological function of the diaphragm for augmenting and assisting ventilation. We investigated two actuator geometries, each at two locations superior to the diaphragm. These actuators were tested on a bespoke ex vivo testbed that accurately simulated key diaphragmatic characteristics throughout the respiratory cycle. From this, we have been able to drive intrathoracic pressures greater than the 5 cmH2O required for ventilation in a human male. Additionally, by optimising the placement and geometry of these soft robotic actuators we have been able to generate maximum intrathoracic pressures of (6.81 ± 0.39) cmH2O.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 The Author(s). |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Electronic Engineering (York) |
Funding Information: | Funder Grant number THE ROYAL SOCIETY RGS\R2\222342 EPSRC EP/R51181X/1 |
Depositing User: | Pure (York) |
Date Deposited: | 14 Aug 2024 11:10 |
Last Modified: | 26 Feb 2025 00:09 |
Published Version: | https://doi.org/10.1016/j.birob.2024.100172 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.birob.2024.100172 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:216136 |
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Description: Design and optimisation of soft robotic actuators for augmented lung-ventilation
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