Shahid-Fuente, I.W. and Toseland, C.P. orcid.org/0000-0002-1641-7535 (2023) Myosin in chromosome organisation and gene expression. Biochemical Society Transactions, 51 (3). pp. 1023-1034. ISSN 0300-5127
Abstract
The importance of myosin motor protein is well-characterised within the cytoplasm and cytoskeleton. However, mounting evidence on four nuclear myosins highlights the central role these proteins have in maintaining genomic stability and gene expression. This review focuses on each of their critical roles in chromatin structure, chromosome translocation, transcription regulation, and DNA damage repair in terms of maintaining chromosome and chromatin integrity.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | gene expression; myosin; nuclear myosin; transcription; Cell Nucleus; Chromatin; Chromosomes; Gene Expression; Myosins; Humans; Animals |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Funding Information: | Funder Grant number MEDICAL RESEARCH COUNCIL MR/M020606/2 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Aug 2024 14:05 |
Last Modified: | 13 Aug 2024 14:05 |
Published Version: | http://dx.doi.org/10.1042/bst20220939 |
Status: | Published |
Publisher: | Portland Press Ltd. |
Refereed: | Yes |
Identification Number: | 10.1042/bst20220939 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:215738 |